In 2024-2025, the support of a Master 2 course by CY Transfer enabled a student from the University of Ferrara (Italy), Daniela CAZZATO to work on her master's thesis.
This project focuses on neurodegenerative diseases These include Alzheimer's and Parkinson's. accumulation of toxic proteins in the brain. In order to better understand this phenomenon, collaboration has been established between CY Cergy Paris University (CYPeptLab platform), specialized in peptide synthesis, and the Fondazione Bietti of Rome, expert in neurodegenerative diseases and proteomics.
Thanks to this complementarity, several fragments of proteins linked to these pathologies were synthesized and studied. Some of them have proved capable of disrupting proteasome activity, a "cell machine" to remove damaged proteins.
This international collaboration has enabled developing new tools to better understand the inflammatory mechanisms associated with these diseases, thus paving the way for new therapeutic pathwayss.
Following this experience, Daniela CAZZATO will begin a PhD at Tor Vergata University in Rome, funded by an Italian medical foundation, in November to continue her research in collaboration with the PeptLab platform.
With financial support from CY Transfer, the platform CYPeptLab was able to make an essential contribution to a medical research project of great scientific value, while strengthening its international relations with a well-known European Institute for Research and Care, specialized in the diagnosis and treatment of ophthalmic diseases.
It should also be stressed that the support and training of young researchers are an integral part of CYPeptLab's missions. It is in this spirit that the laboratory will continue to accompany Daniela throughout her doctorate at Tor Vergata University in Rome.
Such a project could not have come into being without the decisive financial support of CY Transfer
Elisa Peroni, director of Peptlab and Enseignate researcher at BioCIS
